Email this article Inflammatory Rasch-built Overall Disability Scale (I-RODS) for patients with Guillain–Barré syndrome, chronic inflammatory demyelinating polyneuropathy and polyneuropathy with monoclonal gammopathy of undetermined significance: linguacultural ratification in Russia for patients with chronic inflammatory demyelinating polyneuropathy
- Authors: Suponeva N.A.1, Arestova A.S.1, Melnik Е.А.2, Zimin A.A.1,3, Narbut A.M.1, Yakubu А.4, Shcherbakova E.S.1, Zaytsev A.B.5, Grishina D.A.1, Yusupova D.G.1, Gnedovskaya E.V.1, Piradov M.A.1
-
Affiliations:
- Research Center of Neurology
- Research Centre for Medical Genetics
- N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
- Columbia University
- I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
- Issue: Vol 15, No 4 (2025)
- Pages: 17-23
- Section: ORIGINAL REPORTS
- Published: 06.03.2026
- URL: https://nmb.abvpress.ru/jour/article/view/680
- DOI: https://doi.org/10.17650/2222-8721-2025-15-4-17-23
- ID: 680
Cite item
Full Text
Abstract
Background. Chronic inflammatory demyelinating polyneuropathy (CIDP) is the most common type of dysimmune neuropathy, and it can lead to either permanent or temporary disability in about half of patients. Objective assessment of functional impairment is essential for monitoring therapeutic outcomes and disease progression in CIDP. The Inflammatory Rasch-built Overall Disability Scale (I-RODS) is one of the most valuable tools for assessing disability in CIDP patients and can be used in both clinical research and routine practice. In this article, we present the results of the validation process for this scale in Russian individuals with CIDP.
Aim. To translate and validate the I-RODS for use in Russian patients with CIDP.
Materials and methods. The study enrolled 50 cases of CIDP, evenly distributed between the typical variant and Lewis–Sumner syndrome. We performed linguocultural adaptation of the original version of the I-RODS using a standard protocol, after which we assessed the psychometric properties of the Russian version (i.e., its sensitivity, reliability and validity).
Results. Psychometric evaluation demonstrated good reliability, sensitivity, and validity of the Russian I-RODS adaptation.
Conclusion. We validated the Russian-language adaptation of the I-RODS, which can be applied in for both clinical practice and research.
About the authors
N. A. Suponeva
Research Center of Neurology
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0003-3956-6362
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367
Alina S. Arestova
Research Center of Neurology
Author for correspondence.
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0002-9890-3552
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367
Е. А. Melnik
Research Centre for Medical Genetics
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0001-5436-836X
Russian Federation, 1 Moskvorechye St., Moscow, 115522
A. A. Zimin
Research Center of Neurology; N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0002-9226-2870
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367; 1 Ostrovityanova St., Moscow, 117513
A. M. Narbut
Research Center of Neurology
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0003-2026-5199
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367
А. Yakubu
Columbia University
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0001-5434-4966
United States, 116th Street and Broadway, New York, 10027
E. S. Shcherbakova
Research Center of Neurology
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0002-1706-089X
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367
A. B. Zaytsev
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0003-3774-3070
Russian Federation, Build. 2, 8 Trubetskaya St., Moscow, 119991
D. A. Grishina
Research Center of Neurology
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0002-7924-3405
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367
D. G. Yusupova
Research Center of Neurology
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0002-5826-9112
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367
E. V. Gnedovskaya
Research Center of Neurology
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0001-6026-3388
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367
M. A. Piradov
Research Center of Neurology
Email: rizvanova.alina@gmail.com
ORCID iD: 0000-0002-6338-0392
Russian Federation, 80 Volokolamskoe Shosse, Moscow, 125367
References
- Van den Bergh P.Y.K, Hadden R.D., Bouche P. et al. European Federation of Neurological Societies; Peripheral Nerve Society. European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society – first revision. Eur J Neurol 2010;17(3):356–63. doi: 10.1111/j.1468-1331.2009.02930.x
- Ikeda S., Koike H., Nishi R. et al. Clinicopathological characteristics of subtypes of chronic inflammatory demyelinating polyradiculoneuropathy. J Neurol Neurosurg Psychiatry 2019;90(9):988–96. doi: 10.1136/jnnp-2019-320741
- Van den Bergh P.Y.K., van Doorn P.A., Hadden R.D.M et al. European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force-second revision. J Peripher Nerv Syst 2021;26(3):242–68. doi: 10.1111/jns.12455.
- Oaklander A.L., Gimigliano F. Are the treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) effective and safe? A Cochrane overview summary with commentary. Neurorehabilitation 2019;44(4):609–12. doi: 10.3233/NRE-189007
- Allen J.A., Lewis R.A. CIDP diagnostic pitfalls and perception of treatment benefit. Neurology 2015;85(6):498–504. doi: 10.1212/WNL.0000000000001833
- World Health Organization. Towards a common language for functioning, disability and health (ICF), 2001. Available at: http://www.who.int/classifications/icf/en/.
- Merkies I.S., Lauria G. 131st ENMC international workshop: selection of outcome measures for peripheral neuropathy clinical trials. Neuromuscul Disord 200;16(2):149–56. doi: 10.1016/j.nmd.2005.12.003
- Hughes R., Bensa S., Willison H. et al. Inflammatory Neuropathy Cause and Treatment (INCAT) Group. Randomized controlled trial of intravenous immunoglobulin versus oral prednisolone in chronic inflammatory demyelinating polyradiculoneuropathy. Ann Neurol 2001;50(2):195–201. doi: 10.1002/ana.1088
- Allen J.A., Gelinas D.F., Lewis R.A. et al. Optimizing the use of outcome measures in chronic inflammatory demyelinating polyneuropathy. US Neurol 2017;13(1):26–34. doi: 10.17925/USN.2017.13.01.26
- Van Nes S.I., Vanhoutte E.K., van Doorn P.A. et al. Rasch-built Overall Disability Scale (R-ODS) for immune-mediated peripheral neuropathies. Neurology 2011;76(4):337–45. doi: 10.1212/WNL.0b013e318208824b.
- Vanhoutte E.K., Faber C.G., Merkies I.S. et al. 196th ENMC international workshop: outcome measures in inflammatory peripheral neuropathies. 8–10 February 2013, Naarden, the Netherlands. Neuromuscul Disord 2013;23(11):924–33. doi: 10.1016/j.nmd.2013.06.006
- Peric S., Bozovic I., Pruppers M.H.J. et al. Validation of the Serbian version of Inflammatory Rasch-built Overall Disability Scale in patients with chronic inflammatory demyelinating polyradiculoneuropathy. J Peripher Nerv Syst 2019;24(3):260–7. doi: 10.1111/jns.12343
- Novik A.A., Ionova T.I. The manual for the quality-of-life evaluation in medicine. Moscow: ZAO “Olma Media Grupp”, 2007. 320 p. (In Russ.).
- Beaton D., Bombardier C., Guillemin F. et al. Recommendations for the cross-cultural adaptation of health status measures. New York: American Academy of Orthopaedic Surgeons, 2002. Pp. 1–9.
- Kadam P., Bhalerao S. Sample size calculation. Int J Ayurveda Res 2010;1(1):55. doi: 10.4103/0974-7788.59946
- Pelouto F., Baars A.E., Papri N. et al. Patient-reported outcome measures for assessing health-related quality of life in patients with polyneuropathies, focusing on Guillain–Barré syndrome and chronic inflammatory demyelinating polyneuropathy: a systematic review of measurement properties. J Peripher Nerv Syst 2025;30(2):e70022. doi: 10.1111/jns.70022
Supplementary files
