Ultrastructural muscle and neuro-muscular junction alterations in polymyositis
https://doi.org/10.17650/2222-8721-2012-0-2-52-58
Abstract
Ultrastructural analysis of 7 biopsies from m.palmaris longus and m.deltoideus in patients with confirmed polymyositis revealed alteration
and degeneration of muscle fibers and anomalies of neuro-muscular junction (NMJ). The NMJ abnormalities and following denervation of
muscle fibers in polymyositis start with subsynaptic damages. The occurance of regeneration features in muscle fibers at any stage is characteristic for PM.
About the Authors
L. L. Babakova
The Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
O. M. Pozdnyakov
The Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Babakova L.L., Pozdnyakov O.M. Ultrastructural muscle and neuro-muscular junction alterations in polymyositis. Neuromuscular Diseases. 2012;(2):52-58. (In Russ.) https://doi.org/10.17650/2222-8721-2012-0-2-52-58
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