<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Neuromuscular Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Neuromuscular Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Нервно-мышечные болезни</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-8721</issn><issn publication-format="electronic">2413-0443</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">11</article-id><article-id pub-id-type="doi">10.17650/2222-8721-2014-0-1-48-61</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Use of ketonal in lumbago</article-title><trans-title-group xml:lang="ru"><trans-title>Применение кетонала при поясничной боли</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kamchatnov</surname><given-names>P. R.</given-names></name><name xml:lang="ru"><surname>Камчатнов</surname><given-names>П. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>pavkam7@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Umarova</surname><given-names>Kh. Ya.</given-names></name><name xml:lang="ru"><surname>Умарова</surname><given-names>Х. Я.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University, Moscow</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «РНИМУ им. Н.И. Пирогова», Москва</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Chechen State University, Grozny</institution></aff><aff><institution xml:lang="ru">Чеченский государственный университет, Грозный</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-04-19" publication-format="electronic"><day>19</day><month>04</month><year>2014</year></pub-date><volume>4</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>47</fpage><lpage>53</lpage><history><date date-type="received" iso-8601-date="2015-02-19"><day>19</day><month>02</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-02-19"><day>19</day><month>02</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Kamchatnov P.R., Umarova K.Y.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Камчатнов П.Р., Умарова Х.Я.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Kamchatnov P.R., Umarova K.Y.</copyright-holder><copyright-holder xml:lang="ru">Камчатнов П.Р., Умарова Х.Я.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://nmb.abvpress.ru/jour/article/view/11">https://nmb.abvpress.ru/jour/article/view/11</self-uri><abstract xml:lang="en"><p>Lumbago is one of the most common musculoskeletal pain syndromes. The course of lumbago shows a tendency towards frequent relapses and is associated with the significant material costs of medical care. A wide range of analgesics, nonsteroidal anti-inflammatory drugs in particular, whose administration may be linked with an increased risk for adverse visceral reactions, is used to treat patient with lumbago. The risk of their side effects may be reduced by the extensive use of non-drug treatments and the early expansion of a motor regimen in a patient. Therapeutic effectiveness in reducing the likelihood of adverse reactions may be provided by short-term treatment with effective drugs. The advantages of using ketoprofen (ketonal) formulations in patients with lumbago are considered.</p></abstract><trans-abstract xml:lang="ru"><p>Поясничная боль (ПБ) – один из наиболее распространенных скелетно-мышечных болевых синдромов. Течение ПБ характеризуется склонностью к частому рецидивированию и связано со значительными материальными затратами на оказание медицинской помощи. При лечении пациентов с ПБ применяется широкий спектр противоболевых лекарственных средств, в частности нестероидных противовоспалительных препаратов. Назначение последних может быть связано с повышением риска развития нежелательных побочных эффектов со стороны внутренних органов. Снижение риска развития нежелательных эффектов возможно при широком использовании немедикаментозных методов лечения и раннем расширении двигательного режима больного. Обеспечение эффективности терапии при снижении вероятности развития побочных эффектов возможно при проведении относительно коротких курсов лечения эффективными препаратами. Рассматриваются преимущества применения лекарственных форм кетопрофена (кетонал) у пациентов с ПБ.</p></trans-abstract><kwd-group xml:lang="en"><kwd>lumbago</kwd><kwd>treatment</kwd><kwd>side effects</kwd><kwd>ketoprofen</kwd><kwd>ketonal</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>поясничная боль</kwd><kwd>лечение</kwd><kwd>побочные эффекты</kwd><kwd>кетопрофен</kwd><kwd>кетонал</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Parsons S., Breen A., Foster N. et al. Prevalence and comparative troublesomeness by age of musculoskeletal pain in different body locations. Fam Pract 2007;24:308–16.</mixed-citation><mixed-citation xml:lang="ru">Parsons S., Breen A., Foster N. et al. Prevalence and comparative troublesomeness by age of musculoskeletal pain in different body locations. Fam Pract 2007;24:308–16.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Hall H., McIntosh G. Low back pain (acute) Clin Evid 2008;2008:1102–8.</mixed-citation><mixed-citation xml:lang="ru">Hall H., McIntosh G. Low back pain (acute) Clin Evid 2008;2008:1102–8.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Schneider S., Schmitt H., Zoller S., Schiltenwolf M. Workplace stress, lifestyle and social factors as correlates of back pain: a representative study of the German working population. Int Arch Occup Environ Health. 2005;78(4):253–69.</mixed-citation><mixed-citation xml:lang="ru">Schneider S., Schmitt H., Zoller S., Schiltenwolf M. Workplace stress, lifestyle and social factors as correlates of back pain: a representative study of the German working population. Int Arch Occup Environ Health. 2005;78(4):253–69.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Croft P. Is life becoming more of a pain? BMJ 2000;320:1552–3.</mixed-citation><mixed-citation xml:lang="ru">Croft P. Is life becoming more of a pain? BMJ 2000;320:1552–3.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Mafi J.N., McCarthy E.P., Davis R.B., Landon B.E. Worsening trends in the management and treatment of back pain. JAMA Intern Med 2013;173:1573.</mixed-citation><mixed-citation xml:lang="ru">Mafi J.N., McCarthy E.P., Davis R.B., Landon B.E. Worsening trends in the management and treatment of back pain. JAMA Intern Med 2013;173:1573.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Freburger J., Holmes G., Agans R. et al. The rising prevalence of chronic low back pain. Arch Intern Med. 2009;169:251–258.</mixed-citation><mixed-citation xml:lang="ru">Freburger J., Holmes G., Agans R. et al. The rising prevalence of chronic low back pain. Arch Intern Med. 2009;169:251–258.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Kim T., Montejano L., Cao Z., Zhao Y. Health care costs in US patients with and without a diagnosis of osteoarthritis. J Pain Res 2012;5:23–30.</mixed-citation><mixed-citation xml:lang="ru">Kim T., Montejano L., Cao Z., Zhao Y. Health care costs in US patients with and without a diagnosis of osteoarthritis. J Pain Res 2012;5:23–30.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Есин Р.Г., Есин О.Р., Ахмадеева Г.Д., Салихова Г.В. Боль в спине. Казань, 2010. 272 с.</mixed-citation><mixed-citation xml:lang="ru">Есин Р.Г., Есин О.Р., Ахмадеева Г.Д., Салихова Г.В. Боль в спине. Казань, 2010. 272 с.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. Okumura T., Ohhira M., Kumei S., Nozu T. A higher frequency of lumbar ossification of the posterior longitudinal ligament in elderly in an outpatient clinic in Japan. Int J Gener Med 2013;6:729–32.</mixed-citation><mixed-citation xml:lang="ru">Okumura T., Ohhira M., Kumei S., Nozu T. A higher frequency of lumbar ossification of the posterior longitudinal ligament in elderly in an outpatient clinic in Japan. Int J Gener Med 2013;6:729–32.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. Никифоров А.С., Авакян Г.Н. Неврологические осложнения остеохондроза позвоночника. М.: Медпрактика, 2011. 256 с.</mixed-citation><mixed-citation xml:lang="ru">Никифоров А.С., Авакян Г.Н. Неврологические осложнения остеохондроза позвоночника. М.: Медпрактика, 2011. 256 с.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11. Delitto A., George S., Van Dillen L. et al. Low Back Pain. Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability, and Health from the Orthopaedic Section of the American Physical Therapy Association. J Orthop Sports Phys Ther 2012;42(4):A1–57.</mixed-citation><mixed-citation xml:lang="ru">Delitto A., George S., Van Dillen L. et al. Low Back Pain. Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability, and Health from the Orthopaedic Section of the American Physical Therapy Association. J Orthop Sports Phys Ther 2012;42(4):A1–57.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12. Данилов А.Б., Курганова Ю.М. Офисный синдром. РМЖ. Неврология 2012;8;1902–8.</mixed-citation><mixed-citation xml:lang="ru">Данилов А.Б., Курганова Ю.М. Офисный синдром. РМЖ. Неврология 2012;8;1902–8.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13. Poitras S., Durand M., Côté A., Tousignant M. Guidelines on low back pain disability: interprofessional comparison of use between general practitioners, occupational therapists, and physiotherapists. Spine (Phila Pa 1976) 2012;37(14):1252–9.</mixed-citation><mixed-citation xml:lang="ru">Poitras S., Durand M., Côté A., Tousignant M. Guidelines on low back pain disability: interprofessional comparison of use between general practitioners, occupational therapists, and physiotherapists. Spine (Phila Pa 1976) 2012;37(14):1252–9.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14. Montero-Marin J., Garcia-Campayo J., Fajo-Pascual M. et al. Sociodemographic and occupational risk factors associated with the development of different burnout types: the cross–sectional University of Zaragoza study. BMC Psychiatry 2011;11:49–54.</mixed-citation><mixed-citation xml:lang="ru">Montero-Marin J., Garcia-Campayo J., Fajo-Pascual M. et al. Sociodemographic and occupational risk factors associated with the development of different burnout types: the cross–sectional University of Zaragoza study. BMC Psychiatry 2011;11:49–54.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15. Carter Р. 2013 was a horrible year for nursing—nurses are “burnt out”. BMJ 2014;348:g126 doi: 10.1136/bmj.g126.</mixed-citation><mixed-citation xml:lang="ru">Carter Р. 2013 was a horrible year for nursing—nurses are “burnt out”. BMJ 2014;348:g126 doi: 10.1136/bmj.g126.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16. Scott N., Moga C., Harstall C. Managing low back pain in the primary care setting: The know-do gap. Pain Res Manage 2010;15(6):392–400.</mixed-citation><mixed-citation xml:lang="ru">Scott N., Moga C., Harstall C. Managing low back pain in the primary care setting: The know-do gap. Pain Res Manage 2010;15(6):392–400.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">17. Williams C., Henschke N., Maher C. et al. Red flags to screen for vertebral fracture in patients presenting with low-back pain. Cochrane Database Syst Rev 2013 Jan 31;1:CD008643.</mixed-citation><mixed-citation xml:lang="ru">Williams C., Henschke N., Maher C. et al. Red flags to screen for vertebral fracture in patients presenting with low-back pain. Cochrane Database Syst Rev 2013 Jan 31;1:CD008643.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">18. Wertli M., Ruchti K., Steurer J., Held U. Diagnostic indicators of non-cardiovascular chest pain: a systematic review and metaanalysis. BMC Med. 2013 Nov 8;11:239. doi: 10.1186/1741-7015-11-239.</mixed-citation><mixed-citation xml:lang="ru">Wertli M., Ruchti K., Steurer J., Held U. Diagnostic indicators of non-cardiovascular chest pain: a systematic review and metaanalysis. BMC Med. 2013 Nov 8;11:239. doi: 10.1186/1741-7015-11-239.</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">19. McCormack K., Urquhart E. Correlation between nonsteroidal anti-inflammatory drug efficacy in a clinical pain model and the dissociation of their anti-inflammatory and analgesic properties in animal models. Drug Invest 1995;9:88–97.</mixed-citation><mixed-citation xml:lang="ru">McCormack K., Urquhart E. Correlation between nonsteroidal anti-inflammatory drug efficacy in a clinical pain model and the dissociation of their anti-inflammatory and analgesic properties in animal models. Drug Invest 1995;9:88–97.</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">20. Coxib and traditional NSAID Trialists' (CNT) Collaboration. Vascular and upper gastrointestinal effects of non-steroidal antiinflammatory drugs: meta-analyses of individual participant data from randomised trials. The Lancet, Early Online Publication, 30 May 2013; doi:10.1016/S0140- 6736(13)60900-9.</mixed-citation><mixed-citation xml:lang="ru">Coxib and traditional NSAID Trialists' (CNT) Collaboration. Vascular and upper gastrointestinal effects of non-steroidal antiinflammatory drugs: meta-analyses of individual participant data from randomised trials. The Lancet, Early Online Publication, 30 May 2013; doi:10.1016/S0140- 6736(13)60900-9.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">21. McGettigan P., Henry D. Cardiovascular risk and inhibition of cyclooxygenase. A systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase. JAMA 2006;296;13:1–12.</mixed-citation><mixed-citation xml:lang="ru">McGettigan P., Henry D. Cardiovascular risk and inhibition of cyclooxygenase. A systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase. JAMA 2006;296;13:1–12.</mixed-citation></citation-alternatives></ref><ref id="B22"><label>22.</label><citation-alternatives><mixed-citation xml:lang="en">22. Камчатнов П.Р., Чугунов А.В., Трубецкая Е.А. Пациент с болью в спине: возможности терапии. Нервно-мышечные болезни 2013;2:20–7.</mixed-citation><mixed-citation xml:lang="ru">Камчатнов П.Р., Чугунов А.В., Трубецкая Е.А. Пациент с болью в спине: возможности терапии. Нервно-мышечные болезни 2013;2:20–7.</mixed-citation></citation-alternatives></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">23. Riou B., Plaisance P., Lecomte F. et al. Comparison of two doses of ketoprofen to treat pain: a double-blind, randomized, noninferiority trial. Fundam Clin Pharmacol 2013 Jul 24. doi: 10.1111/j.1472-8206.2012.01072.x.</mixed-citation><mixed-citation xml:lang="ru">Riou B., Plaisance P., Lecomte F. et al. Comparison of two doses of ketoprofen to treat pain: a double-blind, randomized, noninferiority trial. Fundam Clin Pharmacol 2013 Jul 24. doi: 10.1111/j.1472-8206.2012.01072.x.</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><citation-alternatives><mixed-citation xml:lang="en">24. Дамулин И.В. Терапевтические возможности при болях в спине вертеброгенного генеза (применение кетопрофена и другие методы лечения). Журн неврол и психиатр 2014;2:81–6.</mixed-citation><mixed-citation xml:lang="ru">Дамулин И.В. Терапевтические возможности при болях в спине вертеброгенного генеза (применение кетопрофена и другие методы лечения). Журн неврол и психиатр 2014;2:81–6.</mixed-citation></citation-alternatives></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">25. Chou R., Qaseem А., Snow V. et al. Diagnosis and Treatment of Low Back Pain: A Joint Clinical Practice Guideline from the American College of Physicians and the American Pain Society. Ann Intern Med. 2007;147(7):478–91.</mixed-citation><mixed-citation xml:lang="ru">Chou R., Qaseem А., Snow V. et al. Diagnosis and Treatment of Low Back Pain: A Joint Clinical Practice Guideline from the American College of Physicians and the American Pain Society. Ann Intern Med. 2007;147(7):478–91.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
