Neuromuscular DiseasesNeuromuscular DiseasesНервно-мышечные болезни2222-87212413-0443Publishing House ABV Press12710.17650/2222-8721-2015-5-4-10-15LECTURES AND REVIEWSЛЕКЦИИ И ОБЗОРЫCardiac involvement in children with neuro-muscular disordersПоражения сердца при нервно-мышечных заболеваниях у детейArkhipovaE. N.АрхиповаЕ. Н.
Russian Federation
elena.arkhipova@gmail.comDmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of RussiaФГБУ «Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии имени Дмитрия Рогачева» Минздрава России1 Samory Mashela St., Moscow, 117198, RussiaРоссия, 117198, Москва, ул. Саморы Машела, 1161220155410151612201516122015Copyright ©; 2015, Arkhipova E.N.Copyright ©; 2015, Архипова Е.Н.2015Arkhipova E.N.Архипова Е.Н.https://creativecommons.org/licenses/by/4.0https://nmb.abvpress.ru/jour/article/view/127

Many inherited neuromuscular disorders include cardiac involvement as a typical clinical feature. Among the most common of them is the group of muscular dystrophies. Dilated cardiomyopathy, ventricular arrhythmias, atrial fibrillations, atrioventricular and intraventricular conduction abnormalities, and sudden cardiac death are well known pathological findings in Duchenne muscular dystrophies, myotonic dystrophy type I and 2, Emery-Dreifuss muscular dystrophies and different types of limb-girdle muscular dystrophies and other disorders. Detection of cardiac pathology in patients with different muscular dystrophies is possible with ECG, echocardiography and cardiovascular magnetic resonance imaging, which are recommended for screening and early cardioprotective treatment.

Многие нервно-мышечные заболевания часто сочетаются с поражением миокарда. Среди наиболее распространенных из них – группа мышечных дистрофий. Дилатационная кардиомиопатия, желудочковые аритмии, фибрилляции предсердий, нарушения атриовентрикулярной и внутрижелудочковой проводимости, а также внезапная сердечная смерть – хорошо известные симптомы при мышечной дистрофии Дюшенна, миотонической дистрофии 1-го и 2-го типов, мышечной дистрофии Эмери–Дрейфуса и различных вариантах поясно-конечностных мышечных дистрофий. Выявление кардиальной патологии у данных групп пациентов возможно с помощью электрокардиографии, эхокардиографии и магнитно-резонансной томографии сердца, которые рекомендованы в рамках скринингового обследования и раннего кардиопротективного лечения.

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