Neuromuscular DiseasesNeuromuscular DiseasesНервно-мышечные болезни2222-87212413-0443Publishing House ABV Press13010.17650/2222-8721-2015-5-4-32-37LECTURES AND REVIEWSЛЕКЦИИ И ОБЗОРЫSystematics and principles of therapy for depressive disorders in epilepsyСистематика и принципы терапии депрессивных расстройств при эпилепсииUsyukinaM. V.УсюкинаМ. В.
Russian Federation
marina_gnc@mail.ruV.P. Serbsky Federal Medical Research Center for Psychiatry and Narcology, Ministry of Health of RussiaФГБУ «Федеральный медицинский исследовательский центр психиатрии и наркологии им. В.П. Сербского» Минздрава России23 Kropotkinsky Pereulok, Moscow, 119034, RussiaРоссия, 119034, Москва, Кропоткинский пер., 23161220155432371612201516122015Copyright ©; 2015, Usyukina M.V.Copyright ©; 2015, Усюкина М.В.2015Usyukina M.V.Усюкина М.В.https://creativecommons.org/licenses/by/4.0https://nmb.abvpress.ru/jour/article/view/130

Relying on a comprehensive investigation, the author proposes the typology of depressive disorders in epilepsy by identifying ictal, preictal, interictal, and postictal conditions. Risk factors for depressive symptoms are considered. Main approaches to therapy for depressions are offered. Particular emphasis is placed on the normothymic activity of a number of anticonvulsants. Valproates, and depakine in particular, as a normothymic agent are shown to be beneficial in treating affective disorders.

На основании комплексного исследования предложена типология депрессивных расстройств при эпилепсии с выделением иктальных, преиктальных, интериктальных и постиктальных состояний. Рассмотрены факторы риска возникновения депрессивной симптоматики. Предложены основные подходы к терапии депрессий. Особое внимание уделяется нормотимическим действиям ряда антиконвульсантов. Показано преимущество вальпроатов, и особенно депакина как нормотимика, при лечении аффективных расстройств.

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