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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Neuromuscular Diseases</journal-id><journal-title-group><journal-title xml:lang="en">Neuromuscular Diseases</journal-title><trans-title-group xml:lang="ru"><trans-title>Нервно-мышечные болезни</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-8721</issn><issn publication-format="electronic">2413-0443</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">476</article-id><article-id pub-id-type="doi">10.17650/2222-8721-2022-12-1-49-55</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ РАЗБОР</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Informative value of neurophysiological and neuroimaging research methods in the onset of spinal cord myelopathy: literature review and clinical observation</article-title><trans-title-group xml:lang="ru"><trans-title>Информативность диагностической транскраниальной магнитной стимуляции в дебюте сосудистой миелопатии спинного мозга: обзор литературы и клиническое наблюдение</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5142-9400</contrib-id><name-alternatives><name xml:lang="en"><surname>Kanshina</surname><given-names>D. S.</given-names></name><name xml:lang="ru"><surname>Каньшина</surname><given-names>Д. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><bold>Darya Sergeevna Kanshina</bold></p><p>70 Nizhnyaya Pervomayskaya St., Moscow 105203</p><p>22 Bolshaya Polyanka St., Moscow 119180</p></bio><bio xml:lang="ru"><p><bold>Дарья Сергеевна Каньшина</bold></p><p>105203 Москва, ул. Нижняя Первомайская, 70</p><p>119180 Москва, ул. Большая Полянка, 22</p></bio><email>dr.d.kanshina@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3692-2109</contrib-id><name-alternatives><name xml:lang="en"><surname>Surma</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Сурма</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>0 Nizhnyaya Pervomayskaya St., Moscow 105203</p></bio><bio xml:lang="ru"><p>105203 Москва, ул. Нижняя Первомайская, 70</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2382-3387</contrib-id><name-alternatives><name xml:lang="en"><surname>Badamshina</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Бадамшина</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>2 Krymskaya St., Ramenskoe 140103</p></bio><bio xml:lang="ru"><p>140103 Раменское, ул. Крымская, 2</p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2784-302X</contrib-id><name-alternatives><name xml:lang="en"><surname>Bronov</surname><given-names>O. Yu.</given-names></name><name xml:lang="ru"><surname>Бронов</surname><given-names>О. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>0 Nizhnyaya Pervomayskaya St., Moscow 105203</p></bio><bio xml:lang="ru"><p>105203 Москва, ул. Нижняя Первомайская, 70</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Medical and Surgical Center named after N. I. Pirogov, Ministry of Health of the Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медико-хирургический центр им. Н. И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Research Institute of Emergency Pediatric Surgery and Traumatology</institution></aff><aff><institution xml:lang="ru">НИИ неотложной детской хирургии и травматологии</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Medical center «New medical technologies</institution></aff><aff><institution xml:lang="ru">Медицинский центр «Новые медтехнологии»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-02-14" publication-format="electronic"><day>14</day><month>02</month><year>2022</year></pub-date><volume>12</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>49</fpage><lpage>55</lpage><history><date date-type="received" iso-8601-date="2022-02-14"><day>14</day><month>02</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-02-14"><day>14</day><month>02</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Kanshina D.S., Surma M.A., Badamshina E.V., Bronov O.Y.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Каньшина Д.С., Сурма М.А., Бадамшина Е.В., Бронов О.Ю.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Kanshina D.S., Surma M.A., Badamshina E.V., Bronov O.Y.</copyright-holder><copyright-holder xml:lang="ru">Каньшина Д.С., Сурма М.А., Бадамшина Е.В., Бронов О.Ю.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://nmb.abvpress.ru/jour/article/view/476">https://nmb.abvpress.ru/jour/article/view/476</self-uri><abstract xml:lang="en"><p>Vascular myelopathy is a variant of acute or subacute lesions of the spinal cord as a result of circulatory disorders in the local vascular basin or hemodynamic changes in the vessels of distant localization.A clinical case of a patient with vascular myelopathy at the thoracic level is presented, the anamnesis of the disease, the results of examination and instrumental research methods with an assessment of the significance of diagnostic transcranial magnetic stimulation at the onset of the disease are presented.The purpose of this publication is to demonstrate the informative value of diagnostic transcranial magnetic stimulation and magnetic resonance imaging in the onset of vascular myelopathy of the spinal cord.A clinical case of a patient with vascular myelopathy at the thoracic level is presented, the history of the disease, the results of examination and instrumental methods of investigation are considered, with an assessment of the significance of diagnostic transcranial magnetic stimulation in the onset of the disease. A review of the literature was carried out in order to assess the information content of neurophysiological and neuroimaging studies in vascular myelopathy. In patients with onset of spinal cord infarction, the study of motor evoked potentials can demonstrate the involvement of cortico-spinal projections even in the absence of neuroimaging data of their damage during 48 hours.The transcranial magnetic stimulation with the analysis of motor evoked potentials is a reliable tool for diagnosing damage to cortico-spinal projections in the onset of vascular myelopathy.</p></abstract><trans-abstract xml:lang="ru"><p>Сосудистая миелопатия – вариант острого или подострого поражения спинного мозга в результате нарушения кровообращения в местном сосудистом бассейне или гемодинамических сдвигов в сосудах отдаленной локализации.Цель настоящей публикации – продемонстрировать информативность диагностической транскраниальной магнитной стимуляции в дебюте сосудистой миелопатии спинного мозга.Представлен клинический случай пациентки с сосудистой миелопатией на грудном уровне, рассмотрены анамнез заболевания, результаты осмотра и инструментальных методов исследования с оценкой диагностической значимости транскраниальной магнитной стимуляции в дебюте заболевания. Проведен обзор литературы с целью оценки информативности нейрофизиологических и нейровизуализационных исследований при сосудистой миелопатии.Обследование пациентки с дебютом инфаркта спинного мозга продемонстрировало информативность моторных вызванных потенциалов в первые 48 ч болезни как маркера вовлечения кортикоспинальных проекций при отсутствии изменений или неоднозначных изменениях при нейровизуализационном исследовании.Транскраниальная магнитная стимуляция с анализом моторных вызванных потенциалов является информативным инструментом диагностики повреждения кортикоспинальных проекций в дебюте сосудистой миелопатии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>myelopathy</kwd><kwd>cortico-spinal tract</kwd><kwd>transcranial magnetic stimulation</kwd><kwd>magnetic resonance imaging</kwd><kwd>motor evoked potential</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>миелопатия</kwd><kwd>кортикоспинальный тракт</kwd><kwd>транскраниальная магнитная стимуляция</kwd><kwd>магнитно-резонансная томография</kwd><kwd>моторный вызванный потенциал</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">International Classification of Diseases 10 revision (ICD-10). 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