Neuromuscular DiseasesNeuromuscular DiseasesНервно-мышечные болезни2222-87212413-0443Publishing House ABV Press4910.17650/2222-8721-2013-0-2-CLINICAL CASEКЛИНИЧЕСКИЙ РАЗБОРClinical case of the late diagnosis of neurolipomatosis (Dercum’s disease)Клинический случай поздней диагностики нейролипоматоза (болезни Деркума)ShnayderN. A.ШнайдерН. А.
Russian Federation
NASchnaider@yandex.ruKiselevI. A.КиселевИ. А.
Russian Federation
DmitrenkoD. V.ДмитренкоД. В.
Russian Federation
Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation Clinical Hospital Fifty-One, Federal Biomedical Agency of Russia, ZheleznogorskГБОУ ВПО «Красноярский ГМУ им. проф. В.Ф. Войно-Ясенецкого» МЗ РФ ФГБУЗ «Клиническая больница № 51» ФМБА России, ЖелезногорскProf. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian FederationГБОУ ВПО «Красноярский ГМУ им. проф. В.Ф. Войно-Ясенецкого» МЗ РФ200620133245522002201520022015Copyright ©; 2013, Shnayder N.A., Kiselev I.A., Dmitrenko D.V.Copyright ©; 2013, Шнайдер Н.А., Киселев И.А., Дмитренко Д.В.2013Shnayder N.A., Kiselev I.A., Dmitrenko D.V.Шнайдер Н.А., Киселев И.А., Дмитренко Д.В.https://creativecommons.org/licenses/by/4.0https://nmb.abvpress.ru/jour/article/view/49

Dercum’s disease (Dercum’s syndrome, neurolipomatosis) is a rare and inadequately studied chronic disease that is characterized by subcutaneous fatty deposits in different parts of the trunk and accompanied by compression-ischemic neuropathy of the cutaneous branches of peripheral nerves with pain syndrome, pathological fatigue, and obesity. The most common site of subcutaneous deposits is the upper extremities, elbows, anterior abdominal wall, buttocks, thighs, and knees. However, Dercum’s disease is systemic and can be manifested by a wide range of symptoms and it frequently recurs, including after surgical removal of lipomas. The paper presents a case of the late diagnosis of neurolipomatosis in a 23-year-old male. It considers the etiology, pathogenesis, and diagnosis of the disease and current approaches to its treatment. A better understanding of the characteristic clinical syndrome of painful lipomatosis will assist in the early diagnosis of the disease and in the prevention of inadequate therapy cases.

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