Neuromuscular DiseasesNeuromuscular DiseasesНервно-мышечные болезни2222-87212413-0443Publishing House ABV Press50510.17650/2222-8721-2022-12-4-20-28LECTURES AND REVIEWSЛЕКЦИИ И ОБЗОРЫAnemia in patients with inflammatory bowel disease as a risk factor for restless legs syndrome. Literature reviewВоспалительные заболевания кишечника, сопровождающиеся анемией, как фактор риска развития синдрома беспокойных ног. Обзор литературыhttps://orcid.org/0000-0003-4703-0744ZakharovaS. A.ЗахароваС. А.
Russian Federation

Build. 10, 27 Lomonosovskiy Prospect, 119192 Moscow

119192 Москва, Ломоносовский проспект, 27, корп. 10

https://orcid.org/0000-0002-5324-4733KalinkinA. L.КалинкинА. Л.
Russian Federation

Alexander Leonidovich Kalinkin 

Build. 10, 27 Lomonosovskiy Prospect, 119192 Moscow

Александр Леонидович Калинкин  

119192 Москва, Ломоносовский проспект, 27, корп. 10

akalinkin@sleeplab.ruLomonosov Moscow State University Medical Research and Educational CenterМедицинский научно-образовательный центр ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»1312202212420281312202213122022Copyright ©; 2022, Zakharova S.A., Kalinkin A.L.Copyright ©; 2022, Захарова С.А., Калинкин А.Л.2022Zakharova S.A., Kalinkin A.L.Захарова С.А., Калинкин А.Л.https://creativecommons.org/licenses/by/4.0https://nmb.abvpress.ru/jour/article/view/505

Restless legs syndrome (RLS) is a neurological, sensorimotor disorder. It is characterized by the uncomfortable and unpleasant sensations in the legs which begin or worsen during periods of rest, primarily in the evening or night, and are relieved by movement. Central iron deficiency plays a vital role in the pathogenesis of RLS. There is evidence that chronic inflammation is an additional risk factor for RLS. Anemia is the most common complication and extraintestinal manifestation of inflammatory bowel disease, therefore the prevalence of RLS in these patients is a problem of great interest. In addition, inflammatory bowel disease patients’ sleep disturbances directly influence the disease’s clinical course and can be the preclinical marker of exacerbation. It is essential for clinicians to be aware of RLS as a possible reason for sleep disturbance and as a factor that negatively affects the quality of life in inflammatory bowel disease patients.

Синдром беспокойных ног (СБН) – это неврологическое сенсомоторное заболевание, характеризующееся неприятными ощущениями в нижних конечностях, которые возникают преимущественно в покое, в вечернее или ночное время суток и облегчаются при движении. Важную роль в патогенезе СБН играет дефицит железа в центральной нервной системе. Есть данные о том, что фактором риска развития СБН также является хроническое воспаление. Анемия – самое частое осложнение и внекишечное проявление воспалительных заболеваний кишечника, поэтому вопрос распространенности СБН у данной группы пациентов представляет особый интерес. При этом нарушения сна у пациентов с воспалительными заболеваниями кишечника влияют на течение основного заболевания и могут являться доклиническими маркерами обострения. Необходимо помнить о СБН как о возможной причине нарушения сна и снижения качества жизни у данной группы пациентов.

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