Neuromuscular DiseasesNeuromuscular DiseasesНервно-мышечные болезни2222-87212413-0443Publishing House ABV Press7110.17650/2222-8721-2012-0-1-25-31CLINICAL REPORTSКЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯThe prevalence and risk factors of diabetic polyneuropathy in inpatients with type 1 diabetesРаспространенность и факторы риска развития диабетической полиневропатии у стационарных больных сахарным диабетом 1-го типаStrokovI. A.СтроковИ. А.
Russian Federation
strigoral@mail.ruMelnichenkoG. A.МельниченкоГ. А.
Russian Federation
AlbekovaZh. S.АльбековаЖ. С.
Russian Federation
ZilovA. V.ЗиловА. В.
Russian Federation
AkhmedzhanovaL. T.АхмеджановаЛ. Т.
Russian Federation
Department of Nervous Diseases, I.I. Sechenov First Moscow State Medical UniversityКафедра нервных болезней Первого МГМУ им. И.М. СеченоваDepartment of Endocrinology, I.I. Sechenov First Moscow State Medical Universityкафедра эндокринологии Первого МГМУ им. И.М. Сеченова200220122125312002201520022015Copyright ©; 2012, Strokov I.A., Melnichenko G.A., Albekova Z.S., Zilov A.V., Akhmedzhanova L.T.Copyright ©; 2012, Строков И.А., Мельниченко Г.А., Альбекова Ж.С., Зилов А.В., Ахмеджанова Л.Т.2012Strokov I.A., Melnichenko G.A., Albekova Z.S., Zilov A.V., Akhmedzhanova L.T.Строков И.А., Мельниченко Г.А., Альбекова Ж.С., Зилов А.В., Ахмеджанова Л.Т.https://creativecommons.org/licenses/by/4.0https://nmb.abvpress.ru/jour/article/view/71

The NISLL scale and 7 electrophysiological tests were used to diagnose distal symmetric sensorimotor polyneuropathy in 120 inpatients with type 1 diabetes mellitus. The high rate (68.3%) of symptomatic or subclinical polyneuropathy was found. The duration of metabolic disturbances rather than short-term fluctuations in glycemia in terms of HbA1c levels was shown to mainly affect the degree of polyneuropathy in the patients of this group. The additional risk factors of polyneuropathy were retinopathy, smoking or hyperlipidemia.

У лечившихся в стационаре больных сахарным диабетом 1-го типа (n = 120) проведена диагностика дистальной симметричной сенсорно-моторной полиневропатии с использованием шкалы NISLL и 7 электрофизиологических тестов. Выявлена высокая частота симптомной или субклинической полиневропатии (68,3 %). Показано, что основное влияние на выраженность полиневропатии у больных данной группы оказывает длительность нарушений метаболизма, но не кратковременные колебания гликемии по показателю HbA1c. Дополнительными факторами риска развития полиневропатии являлись наличие ретинопатии, курениеи гиперлипидемия.

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