Neuromuscular DiseasesNeuromuscular DiseasesНервно-мышечные болезни2222-87212413-0443Publishing House ABV Press7810.17650/2222-8721-2012-0-2-40-51ORIGINAL STUDIESОРИГИНАЛЬНЫЕ СТАТЬИSpecific features of chronic inflammatory demyelinating polyneuropathy in childrenОсобенности хронической воспалительной демиелинизирующей полинейропатии у детейKurenkovA. L.КуренковА. Л.
Russian Federation
alkurenkov@gmail.comNikitinS. S.НикитинС. С.
Russian Federation
BursagovaB. I.БурсаговаБ. И.
Russian Federation
KuzenkovaL. M.КузенковаЛ. М.
Russian Federation
Research Center of Child Health, Russian Academy of Medical SciencesФБГУ Научный центр здоровья детей РАМНResearch Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, MoscowНИИ общей патологии и патофизиологии РАМН, Москва200420122240512002201520022015Copyright ©; 2012, Kurenkov A.L., Nikitin S.S., Bursagova B.I., Kuzenkova L.M.Copyright ©; 2012, Куренков А.Л., Никитин С.С., Бурсагова Б.И., Кузенкова Л.М.2012Kurenkov A.L., Nikitin S.S., Bursagova B.I., Kuzenkova L.M.Куренков А.Л., Никитин С.С., Бурсагова Б.И., Кузенкова Л.М.https://creativecommons.org/licenses/by/4.0https://nmb.abvpress.ru/jour/article/view/78

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune peripheral neuropathy that affects both adults and children. The basis for the paper is the analysis of 5 cases of CIDP in children (3 girls and 2 boys) aged 5 to 17 years, followed up for 3 to 6 years. The types of its clinical picture and electromyographic changes at different disease stages are considered in detail. The course of the disease is traced during therapy with corticosteroids and intravenous human immunoglobulin and plasmapheresis. The results of the authors’ observations are compared with those of investigations conducted by other authors. The consideration of the diagnosis of CIDP and its treatment options focuses on that the international standards must be necessarily met to minimize errors in its differential diagnosis and management of these patients, and to make the prognosis for the disease.

Хроническая воспалительная демиелинизирующая полинейропатия (ХВДП) — заболевание периферических нервов аутоиммунной природы, поражающее как взрослых, так и детей. В основу статьи положен анализ 5 случаев ХВДП у детей в возрасте от 5 до 17 лет (3 девочки и 2 мальчика) с продолжительностью наблюдения от 3 до 6 лет. Подробно рассмотрены варианты клинической картины и электромиографических изменений на разных этапах развития заболевания. Прослежено течение заболевания на фоне терапии кортикостероидами, препаратами внутривенного иммуноглобулина человека и при использовании плазмафереза. Результаты собственных наблюдений сопоставляются с исследованиями других авторов. При рассмотрении диагностики и вариантов лечения ХВДП у детей делается акцент на необходимости обязательного соблюдения международных стандартов для минимизации ошибок в дифференциальной диагностике, ведении таких больных и формировании прогноза течения заболевания.

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