Neuromuscular DiseasesNeuromuscular DiseasesНервно-мышечные болезни2222-87212413-0443Publishing House ABV Press910.17650/2222-8721-2014-0-1-30-36ORIGINAL REPORTSОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯMuscle ultrasound imaging in the diagnosis of amyotrophic lateral sclerosisУльтразвуковая визуализация мышц в диагностике бокового амиотрофического склерозаRushkevichYu. N.РушкевичЮ. Н.
Russian Federation
rushkevich@tut.byZabrodetsG. V.ЗабродецГ. В.
Russian Federation
LikhachevS. A.ЛихачевС. А.
Russian Federation
Republican Research and Practical Center for Neurology and Neurosurgery, Minsk, Republic of BelarusРНПЦ неврологии и нейрохирургии, Минск, Республика Беларусь190420144130361902201519022015Copyright ©; 2014, Rushkevich Y.N., Zabrodets G.V., Likhachev S.A.Copyright ©; 2014, Рушкевич Ю.Н., Забродец Г.В., Лихачев С.А.2014Rushkevich Y.N., Zabrodets G.V., Likhachev S.A.Рушкевич Ю.Н., Забродец Г.В., Лихачев С.А.https://creativecommons.org/licenses/by/4.0https://nmb.abvpress.ru/jour/article/view/9

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease. This pathology is characterized by the involvement of central and peripheral motor neurons in the pathological process. One  f the specific symptoms of ALS is fasciculations - involuntary muscle contractions that may occasionally precede the development of muscle weakness and atrophies. This paper summarizes the accumulated practical experience in using muscle ultrasound study in the diagnosis of fasciculations and their prevalence as an early sign of anterior corneal lesion in ALS.

Самой распространенной формой болезни моторного нейрона является боковой амиотрофический склероз (БАС). Данная патология характеризуется вовлечением в патологический процесс центрального и периферического мотонейронов. Одним из специфических симптомов БАС является появление фасцикуляций – непроизвольных мышечных сокращений, которые иногда могут предшествовать развитию мышечной слабости и атрофий. В данной статье обобщен накопленный практический опыт использования ультразвукового исследования мышц в диагностике фасцикуляций и их распространенности как раннего признака переднерогового поражения при БАС.

amyotrophic lateral sclerosisultrasound studmuscle fasciculationsspinal amyotrophycervical myelopathyбоковой амиотрофический склерозультразвуковое исследованиефасцикуляции мышцспинальная амиотрофияцервикальная миелопатия1. Завалишин И.А. Боковой амиотрофический склероз. М., 2009. 272 с.Завалишин И.А. Боковой амиотрофический склероз. М., 2009. 272 с.2. Brooks B.R., Miller R.G., Swash M. et al. World Federation of Neurology Research Group on Motor Neuron Diseases. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:293–299.Brooks B.R., Miller R.G., Swash M. et al. World Federation of Neurology Research Group on Motor Neuron Diseases. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:293–299.3. Maynard F.M., Bracken M.B., Creasey G. et al. International Standards for Neurological and Functional Classification of Spinal Cord Injury. Spinal Cord 1997;35(5):266–74.Maynard F.M., Bracken M.B., Creasey G. et al. International Standards for Neurological and Functional Classification of Spinal Cord Injury. Spinal Cord 1997;35(5):266–74.4. Preston D.C., Shapiro B.E. Electromyography and neuromuscular disorders: clinical-electrophysiologic correlationsl; 2nd ed., Philadelphia: Elsevier, 2005. 685 р.Preston D.C., Shapiro B.E. Electromyography and neuromuscular disorders: clinical-electrophysiologic correlationsl; 2nd ed., Philadelphia: Elsevier, 2005. 685 р.5. Clinical neurophysiology; ed. J.R. Daube, D.I. Rubin. 3rd ed. NY: Oxford University Press, Inc, 2009. 886 р.Clinical neurophysiology; ed. J.R. Daube, D.I. Rubin. 3rd ed. NY: Oxford University Press, Inc, 2009. 886 р.6. Николаев С.Г., Банникова И.Б. Электро-миографическое исследование в клинической практике. Иваново, 1998. 120 с.Николаев С.Г., Банникова И.Б. Электро-миографическое исследование в клинической практике. Иваново, 1998. 120 с.7. Сердюк А.В., Левицкий Г.Н., Скворцова В.И. Изучение денервационно-реиннервационного процесса при болезни двигательного нейрона и доброкачественных заболеваниях мотонейронов. Журн неврол и психиатр 2006;2:37–43.Сердюк А.В., Левицкий Г.Н., Скворцова В.И. Изучение денервационно-реиннервационного процесса при болезни двигательного нейрона и доброкачественных заболеваниях мотонейронов. Журн неврол и психиатр 2006;2:37–43.8. Misawa S., Noto Y., Shibuya K. et al. Ultrasonographic detection of fasciculations markedly increases diagnostic sensitivity of ALS Neurology 2011;77:1532–7.Misawa S., Noto Y., Shibuya K. et al. Ultrasonographic detection of fasciculations markedly increases diagnostic sensitivity of ALS Neurology 2011;77:1532–7.9. Mayans D., Cartwright M.S., Walker F.O. Neuromuscular Ultrasonography: Quantifying Muscle and Nerve Measurements Phys Med Rehabil Clin N Am 2012; 23(1):133–48.Mayans D., Cartwright M.S., Walker F.O. Neuromuscular Ultrasonography: Quantifying Muscle and Nerve Measurements Phys Med Rehabil Clin N Am 2012; 23(1):133–48.10. Mills K.R. Characteristics of fasciculations in amyotrophic lateral sclerosis and the benign fasciculation syndrome. Brain 2010;133:3458–69.Mills K.R. Characteristics of fasciculations in amyotrophic lateral sclerosis and the benign fasciculation syndrome. Brain 2010;133:3458–69.11. Walker F.O., Donofrio P.D., Harpold G.J. et al. Sonographic imaging of muscle contraction and fasciculations: a correlation with electromyography. Muscle Nerve 1990;13:33–9.Walker F.O., Donofrio P.D., Harpold G.J. et al. Sonographic imaging of muscle contraction and fasciculations: a correlation with electromyography. Muscle Nerve 1990;13:33–9.12. Wenzel S., Herrendorf G., Scheel A. et al. Surface EMG and myosonography in the detection of fasciculations: a comparative study. J Neuroimaging 1998;8:148 –54.Wenzel S., Herrendorf G., Scheel A. et al. Surface EMG and myosonography in the detection of fasciculations: a comparative study. J Neuroimaging 1998;8:148 –54.13. Li T.M., Day S.J., Alberman E. et al. Differential diagnosis of motoneurone disease from other neurological conditions. Lancet 1986;2:731–3.Li T.M., Day S.J., Alberman E. et al. Differential diagnosis of motoneurone disease from other neurological conditions. Lancet 1986;2:731–3.14. Okita T., Nodera H., Shibuta Y. et al. Can Awaji ALS criteria provide earlier diagnosis than the revised El Escorial criteria? J Neurol Sci 2011;302:29 –32.Okita T., Nodera H., Shibuta Y. et al. Can Awaji ALS criteria provide earlier diagnosis than the revised El Escorial criteria? J Neurol Sci 2011;302:29 –32.15. Finsterer J., Erdorf M., Mamoli B. et al. Needle electromyography of bulbar muscles in patients with amyotrophic lateral sclerosis: evidence of subclinical involvement. Neurology 1998;51: 1417–22.Finsterer J., Erdorf M., Mamoli B. et al. Needle electromyography of bulbar muscles in patients with amyotrophic lateral sclerosis: evidence of subclinical involvement. Neurology 1998;51: 1417–22.16. Boekestein W.A., Misawa S., Schelhaas H.J. et al. Diagnostic Sensitivity of ALS. Author Response: Neurology 2012;78;370.Boekestein W.A., Misawa S., Schelhaas H.J. et al. Diagnostic Sensitivity of ALS. Author Response: Neurology 2012;78;370.17. Mills K.R. Detecting fasciculations in amyotrophic lateral sclerosis: duration of observation required. J Neurol Neurosurg Psychiatry 2011;82:549–51.Mills K.R. Detecting fasciculations in amyotrophic lateral sclerosis: duration of observation required. J Neurol Neurosurg Psychiatry 2011;82:549–51.