CHRONIC INTOXICATION WITH “LAUGHING GAS” (NITROUS OXIDE) AS A CAUSE OF B12 DEFICIENCY MYELOPOLYNEUROPATHY IN YOUNG ADULTS

N. A. Suponeva; Супонева Н. А.; D. A. Grishina; Гришина Д. А.; L. A. Legostaeva; Легостаева Л. А.; E. G. Mochalova; Мочалова Е. Г.

doi:10.17650/2222-8721-2016-6-4-37-45

CHRONIC INTOXICATION WITH “LAUGHING GAS” (NITROUS OXIDE) AS A CAUSE OF B12 DEFICIENCY MYELOPOLYNEUROPATHY IN YOUNG ADULTS

Authors: Suponeva N.A.¹, Grishina D.A.¹, Legostaeva L.A.¹, Mochalova E.G.¹
Affiliations:
1. Research Center of Neurology
Issue: Vol 6, No 4 (2016)
Pages: 37-45
Section: CLINICAL DISCUSSION
Published: 04.01.2017
URL: https://nmb.abvpress.ru/jour/article/view/178
DOI: https://doi.org/10.17650/2222-8721-2016-6-4-37-45
ID: 178

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Abstract

The problem of using nitrous oxide (“laughing gas”) is now important because young people often prefer this kind of entertainment. Regular short-term inhalation of nitrous oxide increases the risk of developing vitamin B₁₂ deficiency, which is an essential cofactor of important metabolic processes. This article describes 2 clinical cases of neurological disorders in young adults who had used nitrous oxide. We demonstrate difficulties in the diagnosis, therapeutic tactics and prognosis.