Ramsey Hunt syndrome in the child: case report and treatment approach

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Abstract

Herpes zoster is a manifestation of the reactivation of an infection after chickenpox. One of the manifestations of herpes zoster is Ramsey Hunt syndrome, which develops when the ganglion of the VII pair of cranial nerves is involved in process. Diagnosis of Ramsey Hunt syndrome is often based on a combination of a rash in the outer ear and peripheral paresis of the facial muscles. The article describes a rare clinical case of herpes zoster in a child without clinical signs of immunodeficiency, with the development of unilateral paralysis of the facial muscles, pleocytosis in the cerebrospinal fluid. Therapy was performed with a combination of acyclovir and high doses of methylprednisolone with a good clinical effect. It is first mentioning of deviations in the immune status (decreased concentration of the number of markers of naive T‑lymphocytes (TREC)) were revealed, which could be associated with the development of herpes zoster in a child.

About the authors

A. K. Shakaryan

Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences; Pirogov Russian National Research Medical University

Author for correspondence.
Email: 90329764@mail.ru
ORCID iD: 0000-0003-3417-3631

Armen Karenovich Shakaryan 

Build. 1, Home Ownership 8, Pos. Instituta Poliomielita, Moskovskiy Settlement, 108819 Moscow

1 Ostrovityanova St., Moscow 117997

Russian Federation

I. V. Mitrofanova

Infection Disease Hospital № 1

Email: fake@neicon.ru
ORCID iD: 0000-0002-8788-1060

63 Volokolamskoe Shosse, Moscow 125367

Russian Federation

S. V. Shakhgildyan

Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences; Infection Disease Hospital № 1

Email: fake@neicon.ru
ORCID iD: 0000-0003-4717-0931

Build. 1, Home Ownership 8, Pos. Instituta Poliomielita, Moskovskiy Settlement, 108819 Moscow

63 Volokolamskoe Shosse, Moscow 125367

Russian Federation

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Copyright (c) 2021 Shakaryan A.K., Mitrofanova I.V., Shakhgildyan S.V.

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