Navigated transcranial magnetic stimulation possibilities in difficult diagnostic cases upper motor neuron lesions – case report

Cover Page

Cite item

Full Text

Abstract

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized with lesions of both upper and lower motor neurons. In accordance with modern diagnostics criteria, only clinical symptoms are used for revealing lesions of the upper motor neuron with the ALS, which often causes serious difficulties. Absence of the pyramidal syndrome does not allow diagnosing ALS, and the diagnosis of progressive muscular atrophy should be set in these cases. We describe a case of an isolated generalized lesion of the lower motor neuron with the signs of cortical motor neurons lesion revealed in the course of navigational transcranial magnetic stimulation. Possible reasons for difficulties in detecting pyramidal syndrome are discussed together with the necessity of working out the criteria of instrumental diagnostics of lesions of the upper motor neuron in ALS.

About the authors

I. S. Bakulin

Research Center of Neurology

Author for correspondence.
Email: bakulinilya@gmail.com
80, Volokolamskoe Shosse, Moscow, 125367 Russian Federation

A. V. Chervyakov

Research Center of Neurology

Email: bakulinilya@gmail.com
80, Volokolamskoe Shosse, Moscow, 125367 Russian Federation

M. N. Zakharova

Research Center of Neurology

Email: bakulinilya@gmail.com
80, Volokolamskoe Shosse, Moscow, 125367 Russian Federation

N. A. Suponeva

Research Center of Neurology

Email: bakulinilya@gmail.com
80, Volokolamskoe Shosse, Moscow, 125367 Russian Federation

M. A. Piradov

Research Center of Neurology

Email: bakulinilya@gmail.com
80, Volokolamskoe Shosse, Moscow, 125367 Russian Federation

References

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2015 Bakulin I.S., Chervyakov A.V., Zakharova M.N., Suponeva N.A., Piradov M.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 85909 от  25.08.2023.