Bickerstaff brainstem encephalitis, acute transverse myelitis, and acute motor axonal neuropathy: diagnostic and treatment challenges in patients with concomitant syndromes. Clinical observation

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Abstract

We report a 40-year-old woman presented with consciousness disturbance, ataxia, asymmetrical limb weakness, hyperreflexia. Due to magnetic resonance imaging findings, the patient was diagnosed with Bickerstaff’s brainstem encephalitis overlapped with acute transverse myelitis. Later she developed distal muscles atrophy and the electroneuromyographic study revealed axonal motor neuropathy, therefore acute motor axonal neuropathy was diagnosed. The patient underwent one course of intravenous immunoglobulin therapy with the regression of symptoms and magnetic resonance imaging changes. Nine months after symptoms onset, the patient has completely recovered. This overlapping case of Bickerstaff’s brainstem encephalitis, acute transverse myelitis and acute motor axonal neuropathy provides further support that these conditions are part of the same spectrum.

 

About the authors

A. F. Murtazina

Medical Center “Practical Neurology”

Author for correspondence.
Email: aysylumurtazina@gmail.com
Russian Federation

E. S. Naumova

Medical Center “Practical Neurology”

Email: aysylumurtazina@gmail.com
Russian Federation

S. S. Nikitin

Medical Center “Practical Neurology”

Email: aysylumurtazina@gmail.com
Russian Federation

L. M. Boriskina

Normodent Central Clinic

Email: aysylumurtazina@gmail.com
Russian Federation

A. V. Lagutin

Central Clinical Hospital of the Administration of the President of the Russian Federation

Email: aysylumurtazina@gmail.com
Russian Federation

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