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Нервно-мышечные болезни

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Хроническая боль, депрессия и когнитивные нарушения: тесные взаимосвязи


https://doi.org/10.17650/2222-8721-2018-8-3-34-42

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Аннотация

Более половины пациентов с хронической болью (ХБ) предъявляют жалобы на когнитивные нарушения (КН), которые cнижают их трудоспособность и качество жизни. В статье представлен обзор исследований, продемонстрировавших объективные нарушения памяти, внимания, скорости мышления и исполнительной функции при ХБ. Также обсуждаются общие механизмы патогенеза КН и ХБ: нейропластичность в общих зонах головного мозга, нейромедиаторные и другие молекулярные механизмы. Представлен обзор общих патогенетических механизмов депрессии, ХБ и КН. Также приведено сравнение различных антидепрессантов в коррекции КН при депрессии и ХБ.

Об авторах

Н. В. Латышева
ФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России; Клиника головной боли и вегетативных расстройств им. акад. Александра Вейна.
Россия
119991 Москва, ул. Трубецкая, 8, стр. 2; 

125130 Москва, Старопетровский проезд, 10б.



Е. Г. Филатова
ФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России; Клиника головной боли и вегетативных расстройств им. акад. Александра Вейна.
Россия
119991 Москва, ул. Трубецкая, 8, стр. 2; 

125130 Москва, Старопетровский проезд, 10б.



Д. В. Осипова
ФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России.
Россия
119991 Москва, ул. Трубецкая, 8, стр. 2.


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Для цитирования:


Латышева Н.В., Филатова Е.Г., Осипова Д.В. Хроническая боль, депрессия и когнитивные нарушения: тесные взаимосвязи. Нервно-мышечные болезни. 2018;8(3):34-42. https://doi.org/10.17650/2222-8721-2018-8-3-34-42

For citation:


Latysheva N.V., Filatova E.G., Osipova D.V. Chronic pain, depression and cognitive impairment: a close relationship. Neuromuscular Diseases. 2018;8(3):34-42. (In Russ.) https://doi.org/10.17650/2222-8721-2018-8-3-34-42

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