Anemia in patients with inflammatory bowel disease as a risk factor for restless legs syndrome. Literature review
https://doi.org/10.17650/2222-8721-2022-12-4-20-28
Abstract
Restless legs syndrome (RLS) is a neurological, sensorimotor disorder. It is characterized by the uncomfortable and unpleasant sensations in the legs which begin or worsen during periods of rest, primarily in the evening or night, and are relieved by movement. Central iron deficiency plays a vital role in the pathogenesis of RLS. There is evidence that chronic inflammation is an additional risk factor for RLS. Anemia is the most common complication and extraintestinal manifestation of inflammatory bowel disease, therefore the prevalence of RLS in these patients is a problem of great interest. In addition, inflammatory bowel disease patients’ sleep disturbances directly influence the disease’s clinical course and can be the preclinical marker of exacerbation. It is essential for clinicians to be aware of RLS as a possible reason for sleep disturbance and as a factor that negatively affects the quality of life in inflammatory bowel disease patients.
About the Authors
S. A. Zakharova
Lomonosov Moscow State University Medical Research and Educational Center
Russian Federation
Russian Federation
Build. 10, 27 Lomonosovskiy Prospect, 119192 Moscow
A. L. Kalinkin
Lomonosov Moscow State University Medical Research and Educational Center
Russian Federation
Russian Federation
Alexander Leonidovich Kalinkin
Build. 10, 27 Lomonosovskiy Prospect, 119192 Moscow
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Review
For citations:
Zakharova S.A., Kalinkin A.L. Anemia in patients with inflammatory bowel disease as a risk factor for restless legs syndrome. Literature review. Neuromuscular Diseases. 2022;12(4):20-28. (In Russ.) https://doi.org/10.17650/2222-8721-2022-12-4-20-28
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