Electron microscopic study of skeletal muscle in the Lambert–Eaton myasthenic syndrome
https://doi.org/10.17650/2222-8721-2013-0-4-19-23
Abstract
Skeletal muscle biopsies of 7 patients with Lambert–Eaton syndrome were studied. Revealed that specific changes in the neuromuscular junctions are the complication of the postsynaptic region organization. Along with this, there is a destructive process in axon terminals, which may be terminated by the denervation of muscle fibers. Violations of the structure of muscle fibers were observed. A new hypothesis of the Lambert–Eaton syndrome pathogenesis was preposed.
About the Authors
L. L. Babakova
The Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
O. M. Pozdnyakov
The Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Babakova L.L., Pozdnyakov O.M. Electron microscopic study of skeletal muscle in the Lambert–Eaton myasthenic syndrome. Neuromuscular Diseases. 2013;(4):19-23. (In Russ.) https://doi.org/10.17650/2222-8721-2013-0-4-19-23
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