Nerve sonography in multifocal motor neuropathy and chronic inflammatory demyelinating polyneuropathy
https://doi.org/10.17650/2222-8721-2016-6-1-63-73
Abstract
The quantitative ultrasound characteristics (USC) of the median, ulnar nerve at different levels and the spinal nerves in patients with multifocal motor neuropathy (MMN; n=13; 40,4 ± 12,6 years old) and chronic inflammatory demyelinating polyneuropathy (CIDP; n = 7; 47,3 ± 11,2 year old) did not reveal statistical difference in cross sectional area (CSA) between analyzed groups. Patients with MMN have more pronounced asymmetry of CSA in comparison with CIDP patients which have a symmetrical pattern of diffuse nerve involvement. Quantitative USC has shown to be not informative enough in differentiation of MMN and CIDP. The qualitative analysis (QA) according to 3 described types of nerve changes has shown that CIDP is characterized by the prevalence of type 3 pattern (85.8 %) while MMN – by type 2 (69.2 %). The sensitivity and specificity of proposed QA patterns in nerve USC need to be analyzed in additional investigations.
About the Authors
D. S. Druzhinin
Department of Nervous System Diseases with Course of Medical Genetics and Pediatric Neurology, Yaroslavl State Medical University, Ministry of Health of Russia; 6 Revolutionnaya St., Yaroslavl, 150000, Russia;
Russian Federation
Russian Federation
E. S. Naumova
Medical Center “Practical Neurology”, Society of Experts in Neuromuscular Disease; Build. 2, 17 Krzhizhanovsky St., Moscow, 117218, Russia
Russian Federation
Russian Federation
S. S. Nikitin
Medical Center “Practical Neurology”, Society of Experts in Neuromuscular Disease; Build. 2, 17 Krzhizhanovsky St., Moscow, 117218, Russia
Russian Federation
Russian Federation
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Review
For citations:
Druzhinin D.S., Naumova E.S., Nikitin S.S. Nerve sonography in multifocal motor neuropathy and chronic inflammatory demyelinating polyneuropathy. Neuromuscular Diseases. 2016;6(1):63-73. (In Russ.) https://doi.org/10.17650/2222-8721-2016-6-1-63-73
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